Wednesday, February 20, 2019
Histology Detective and Brains Cape Essay
This case matter foc ingestions on the identification of metastatic tissues cells that are come on of place causing neoplasms elsewhere in the body. shit the cells you identify in this sample of lung tissue and the main characteristics that you can use to distinguish them.From the utterance of the sample there are variety of cells which can be place as melanocytes. The main characteristics that can be apply in distinguishing them is their accessory to the stratified squamous epithelial tissue. Moreover, they are large and darker compared to the surrounding calls. Melanocytes are obtusely packed and have only one core.How did you use the main characteristics of several(predicate) tissues that you knowledgeable in your lecture and lab sections as the basis for identifying those cells responsible for the tumor?I applied my histology knowledge from my lectures in distinguishing the features of different cells. I had knowledge on how melanocytes and the natural cells look handle on a slide hence it was very easy distinguishing and describing the cells. The cells under observations were antidromic from their look. They were larger in size, darker in color and round. Moreover. Their nucleus were larger compared to the some other nucleus of the normal cells and has less cytoplasm. The melanocytes on the slide is always darker compared to the normal cells. match to Garbe et al (2010), there exists significant differences between the tumor cells and the autochthonic cells since the tumor cells are widespread in the extracellular fluid, are larger, much darker and more(prenominal) so cube shaped. On the other hand, the native cells are packed densely, smaller, and elongated.In addition to the information in the case presentation (including the net sites contained in the case itself), what other information did you capture to determine the personal identity of the cells and whether one type of cell had migrated from elsewhere in the body? Where did you chance upon this information?What does from each one of these additional tips contribute to the solution of the case? For example, the item contains data from specific tests, trials, or experiments, or presents analyses that can be apply to understand the main issues in this case.The article diagnosing and treatment of malignant malignant melanoma European consensus-based interdisciplinary guideline provided experimental illustrating melanoma components. This affirmed that native cells can be differentiated from the invasive cells by features such as arrangement, form and color. The study used histology in identifying the invasive cells from the non-invasive ones (Garbe et al, 2010).In the NIH article, Diagnosis and treatment of primordial melanoma, majorly the study was based on histology. The study heroic fully developed melanoma and the early melanoma by categorizing their histological features. Moreover, they identified melanoma stages and different types of melanoma w ith application of histology (NIH et al, 1992).In the third gear study, re researcher physicians in two universities in three different melanoma cases of various origins in the body. However, all the characteristics of the abnormal cells were distinguished to be melanocytes. The identified abnormal features of the cells are alike(p) to the ones in this case study, hence proving that the abnormal cells observed in the lung tissue were melanocytes (Sonda et al, 2008).What other findings or information in this case are consistent with the information you located? Name those similarities in each of your additional resources. How do these resources apply what you have learned close to identifying tissues and cells histologically?From the article I reviewed, there was similarity with the case study in many areas. First, all the studies and the case used a similar method in diagnosing melanoma. They applied the cells histological characteristics in determine their status whether they ar e noninvasive or invasive cells. The characteristics identified helped in classification of the cells and in determining their origin.What findings or information in each of the additional resources are not consistent with the findings in this case? Name those differences in each of your additional resources. How do these resources apply what you have learned ab by identifying tissues and cells histologically?In the article Diagnosis and treatment of early melanoma, the study asserted that the cells making melanoma were the stratified melanoma epithelial tissue (NIH et al, 1992). This contradicts the results of the caseIf your proposed resolution of the case is correct, what other observations might we expect to find in this case?Other observations we might find include metastasis of the tumor to other organs hence the patients could suffer from other compounded problems like neurological problems, digestion and bleeding.Give your solution to this case and, on a shell of 15, rate how confident you are in your conclusions in questions 1 and 2I would rate my office at 5 out of 5 because of the observable characteristics of melanomaIn considering your resolution and level of confidence level from question 8, describe how you located the information you used in this case.To begin the search, I started with the most comprehensive data base that is additive Index to Nursing and Allied Health (NINAH) (Kennedy 2009). The search then go on to search engines such as British Nursing Index, MEDLINE. Moreover PubMed and NCBI were other major search engines which assisted some of the pertinent articles. These search engines were used because they contained most of the peer review articles and books. To limit and narrow down the search for articles, internal searches of the databases was used by inserting full length of texts and searching the applicable articles from the list of journals displayed. Moreover, I limited myself to the current articles of up to 5 long ti meWhat you might do differently if you had it to do over again? For example, would you use different resources and strategies? Different information?First, I would use different relevant articles to make companions of different studies. Moreover, I would try using group use to get opinions and arguments of different group member.ReferencesGarbe, C., Peris, K., Hauschild, A., Saiag, P., Middleton, M., Spatz, A., Grob, J. J., Eggermont, A. (January 01, 2010). Diagnosis and treatment of melanoma European consensus-based interdisciplinary guideline. European Journal of Cancer, 46, 2, 270-283. Retrieved from http//www.ncbi.nlm.nih.gov/pubmed/19959353Kennedy, J. R. (2009). Library research guide to schooling illustrated search strategy and sources. Ann Arbor, Mich, Pierian Press.NIH Consensus Development Conference on Diagnosis and manipulation of Early Melanoma, & National Institutes of Health (U.S.). (1992). Diagnosis and treatment of early melanoma. Bethesda, Md U.S. Dept. of Healt h and Human Services, National Institutes of Health, Public Health Service, Office of checkup Applications of Research. Retrieved from http//consensus.nih.gov/1992/1992Melanoma088html.htmSonda, Vemon K., MD, Zager, Jonathan S., MD, Messiana, Jane L., MD. Hemonc today. (2008, Oct 10). Retrieved from http//www.hemonctoday.com/article.aspx?rid=37772Source document
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